eimele

eimele® launches innovative functional

coffee to tackle your metabolism concerns

 

 

 

Throughout life we acquire wisdom and gain experience however as we age, physiologically our body’s metabolism and metabolic rate all start to slow down.  At eimele® a team of experts have created an innovative product that targets this issue by using a blend of functional ingredients that are scientifically proven to optimise your metabolism.

What is Metabolism?

Metabolism is a term used to describe all the different chemical processes/reactions that occur continuously inside your body, that create and break down energy to keep you alive and your organs functioning normally such as breathing, repairing and digesting food.[1]

There are two types of metabolism, one called anabolism, where small molecules are synthesized to make larger ones such as when oxygen and hydrogen combine to form water. The second type of metabolism that occurs is catabolism, where larger molecules are broken down into smaller ones, such as when glucose is broken down into pyruvate which is utilised by our energy system in our body.[2]

Both these chemical reactions require energy and this comes from the breakdown of the food we eat including carbohydrates, proteins and fats, into their simpler forms. In fact up to 70% of the energy used by the body goes toward the very basic processes required to keep you alive. This is known as the basal metabolic rate. How well or how much energy your body needs and burns, is affected by your metabolism.[3]

How fast or slow your metabolism is, is commonly known as metabolic rate[3].  Put simply it is the number of calories/kilojoules (obtained from food) that you burn in a given amount of time. So the faster your metabolism is, the more kilojoules/calories your body needs and burns. Metabolic rate can vary between individuals, some of which is due to your genes but also body size, age, gender, amount of muscle you have and amount of physical activity you do.

 

The helpers in metabolism – enzymes and coenzymes

The metabolic reactions happening inside our body require the help of enzymes to facilitate their actions. Enzymes, which are large protein molecules, function as catalysts by speeding up the rate of the chemical reactions that take place within our cells.[4]

The activities of these enzymes can help in increasing and decreasing the metabolism process in our body. For example, some enzymes help to break down large nutrient molecules such as protein, fats and carbohydrates into smaller molecules that are more easily absorbed by the body, which occurs during digestion. Other enzymes help bind two molecules together to produce a new molecule, such as in protein synthesis.[5]

In many cases, the enzymes need assistants to help them. Enzyme helpers are called coenzymes and they work closely with enzymes to enhance these biological reactions, by binding to them in a lock-and-key type model. Without these coenzymes, an enzyme cannot function efficiently, adversely affecting the metabolic reaction, in question. For example, when the salivary enzyme called amylase binds to a starch (that you’ve just eaten), it catalyzes hydrolysis (the breakdown of a compound due to a reaction with water), resulting in a product called maltose (a type of sugar) [5]. Figure 2 illustrates the enzymatic reaction.

Vitamins as coenzymes

Vitamins, specifically the water-soluble ones, function as coenzymes.  These we must get from our diet because our body cannot synthesize them. In particular are the B group of vitamins, which we get from wholegrains, fish, meats, vegetables, grains, legumes and seeds.

These conenzyme-B vitamins assist the enzymes to release energy from carbohydrates, fats and proteins.[5]

A compound (also called a substrate) is converted to product(s) by a series of enzyme-catalyzed steps, with the help of the coenzymes, in a lock-and-key model.

Vitamin B6 and its role in amino acid metabolism

As discussed, B vitamins act as coenzymes for several enzymatic reactions. In particular is vitamin B6, a key ingredient in eimele® Metabolism Plus Coffee. Vitamin B6 is found in tofu, chickpeas, oats, rice, nuts, potatoes, squash, spinach, watermelon and bananas.[6]

Vitamin B6, in its biologically active coenzyme form, pyridoxal 5’-phosphate (PLP) facilities the function of a large number of essential enzymes, some of which are involved in the metabolism of glucose, lipids (or fats) and amino acids. Specifically it is involved in the synthesis, transformation and degradation of amino acids[7], the building blocks of protein to be utilised by the body.

Supporting evidence for its essential role in metabolism and human health is reflected in how actively it is studied in relationship to a wide range of disease prevention and control.[8]

Vitamin B12 and its role in fatty acid metabolism

Vitamin B12, also an ingredient of eimele® Metabolism Plus Coffee, is a source of coenzymes needed for the metabolism of fatty acids and amino acids.[5]  As Vitamin B12 is bound to protein in food, it must be released in the intestines before it is absorbed. Deficiency may develop due to malabsorption issues in the gut or dietary inadequacy. Vitamin B12 can only be obtained from the diet and is found predominantly in foods of animal origin but also in fortified breakfast cereals, fortified nutritional yeast and a small amount in tempeh. To substantially reduce the risk of deficiency in vegans and vegetarians, it is very important that this at risk group supplement with B12[9]

A recent review in 2020 of several pre-clinical and clinical studies, found that a deficiency of vitamin B12 may be linked to increased fat accumulation supporting its key role in fat metabolism.[10]

Another study, in 2019 looked at the inverse association between vitamin B12 and obesity among adults in the United States. Obesity is a disorder of the energy homeostasis system in the body and dietary components can theoretically affect energy balance by altering energy intake, energy expenditure, or both.  This study also found that individuals with lower vitamin B12 concentrations were more likely to be obese.[11]

Thus, having an adequate intake of vitamin B12 rich-foods may be associated with a lower risk of obesity with a positive effect on fatty acid metabolism.

Biotin and its role in energy metabolism

Biotin, another key B group vitamin and functional ingredient in eimele® Metabolism Plus Coffee, plays an important role in a variety of critical metabolic pathways, by catalysing key reactions in  gluconeogenesis (synthesis of glucose, a sugar to be used as energy by the body), fatty acid synthesis and amino acid catabolism (break down of), in its role as a coenzyme[12]

This is evident in several conditions of biotin deficiency resulting in abnormalities associated with growth and development13. Therefore, biotin homeostasis is crucial for maintaining normal body functions and ultimately converting food into energy that your body needs.

Biotin can be found in nuts (almonds, peanuts, pecans, and walnuts), seeds (sunflower seeds), soybeans, oatmeal, sweet potato, mushrooms, spinach, avocado, broccoli and bananas.  As the body does not store biotin, you need to consume it regularly either through diet or as a supplement to maintain adequate levels.[14]

Summary

Although your metabolism slows down with age, there are many ways to combat this.

Including essential vitamins in your diet, such as the B group vitamins and their coenzymes can help accelerate the metabolic process.

By including scientifically-based functional

ingredients like vitamin B6, vitamin B12 and Biotin into eimele’s new and innovative product they will ensure you are getting that essential and healthy boost to your metabolism.

 

 

www.eimele.com

 

References:

  1. Does Metabolism Matter in Weight Loss? 1.Harvard Medical School (2014)
  2. Ori, J, (2017) What is the role of enzymes in Metabolism. Sciencing
  3. Metabolism (2020). Better Health Victoria Government
  4. Cooper, GM & Sunderland, MA (2000). The Cell: A Molecular Approach. 2nd edition
  5. Whitney, E, Rady Rolfes, S, Crowe, T, Cameron-Smith, D, Walsh, A. (2004). Understanding Nutrition. Cengage Learning Australia. 2nd Editon.National Institutes of Health (2021). Vitamin B6.
  6. Mascolo, E & Verni, F (2020). Vitamin B6 and Diabetes: Relationship and Molecular mechanisms. International  Journal of Molecular Science. May: 21(10):3669.
  7. Mooney, S, Leuendorf, J-E, Hendrickson, C & Hellmann, H (2009). Vitamin B6: A Long Known Compound of Surprising Complexity. Molecules. Jan: 14 (1):329-351.
  8. National Institutes of Health (2021). Vitamin B12.
  9. Boachie, J, Adaikalakoteswari, A, Samavat, J and Saravanan, P (2020). Low Vitamin B12 and Lipid Metabolism: Evidence from Pre-Clinical and Clinical Studies. Nutrients.  Jul; 12(7): 1925.
  10. Sun, Y, Sun, M Liu, B, Du, Rong, S, Xu, G, Snetselaar,L and Bao, W (2019). Inverse Association Between Serum Vitamin B12 Concentration and Obesity Among Adults in the United States. Front Endocrinol (Lausane). 10:414.
  11. Meléndez R. Importance of biotin metabolism. (2000) Rev Invest Clin. March-April;52(2):194-9
  12. Said,H (2012). Biotin: biochemical, physiological and clinical aspects. Sub- cellular biochemistry. 56:1-19.
  13. National Institutes of Health (2021). Biotin