A study recently published highlights the findings from the combination of the two proprietary and well-documented ingredients Bimuno ® GOS and Probi Defendum ® which shown to significantly increase the production of lactate and short-chain fatty acids, specifically butyrate.
There is a rising interest and awareness in health and nutrition, and consumers seek ways to improve their digestive, immune, and overall health. Following probiotic supplements, synbiotic supplements (comprising of 2,900 products on the market today) remain the most developed category. Synbiotics challenges pure probiotics by volume of consumers online engagement which showed a growth of 16% in the first half of 2023. As such, synbiotics supplements have overtaken (pure) probiotic supplements of online engagement in first half of 2023.1 The global synbiotic products market is predicted to continuously grow with a CAGR rate of 7.5% between 2023 to 2030.2
The recently published study shows the superior benefit of combining Clasado’s Bimuno GOS with Probi’s immune strengthening concept, Probi Defendum. The results showed that the probiotic strains L. plantarum HEAL9 (HEAL9™) and L. paracasei 8700:2® were able to utilize the Bimuno GOS for growth, resulting in increased levels of lactate and butyric acid, two well-known health-promoting compounds. This indicates a synergistic synbiotic relationship between these prebiotic and probiotic ingredients. The study also evaluated the combination of Bimuno GOS and Probi´s gut health promoting concept Probi Digestis® which are shown to act as complementary synbiotics, meaning both ingredients are effective and promote their individual health benefits without interaction. This study is thereby one of few scientific studies clearly showing that the combination of probiotics and prebiotics can have a greater benefit than either ingredient alone.
“With our strong foundation in probiotics for gut and immune health, we are happy to demonstrate that we together with our partner Clasado can deliver proven synbiotic solutions with enhanced health benefits. This strengthens our already existing offers, Probi Digestis and Probi Defendum, and broadens our offerings in the biotics area”, says Anita Johansen, CEO Probi AB.
The study “A Novel Synbiotic Blend of Galactooligosaccharide (GOS) and a Two-Strain Probiotic Acts Synergistically to Increase Lactate and Short-Chain Fatty Acid Production in a Short-Term Ex Vivo Colon Fermentation Model” was published in International Journal of Nutritional Sciences (2024) 9 (1), and can be found here: LINK
1 Lumina Intelligence (October 2023): Biotics H1 2023 Key Findings
2 FMI Synbiotics products market size June 2022
3 International Scientific Association for Probiotics and Prebiotics (ISAPP)
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