A study recently published in the Journal of Functional Foods shows that ingestion of the curcumin – cyclodextrin complex CAVACURMIN ® leads to an increased
metabolic bioavailability of tetrahydrocurcumin. A large portion of supplemented curcumin is converted into tetrahydrocurcumin in the body. This metabolite is credited with anti – inflammatory and antioxidant properties. CAVACURMIN ® is the only formulation on the market that demonstrably boosts the bioavailability of both curcumin and tetrahydrocurcumin.
Curcumin, the active compound in turmeric, is a powerful antioxidant that supports healthy aging and joint health , as has been demonstrated in various studies. As it is not water – soluble, curcumin is not readily absorbed in the human bloodstream. Its bioavailability can be boosted significantly with the aid of gamma – cyclodextrin. A study published in 2018 shows that the curcuminoids of WACKER’s cyclodextrin complex CAVACURMIN ® are absorbed around 40 times more efficiently in the
body than those of a standard curcumin extract (Purpura et al. 2018).
As part of a randomized double – blind study, it has now been shown that the metabolic bioavailability of tetrahydrocurcumin is also around 40 times higher following ingestion of CAVACURMIN ® compared to a standard curcumin extract (Hundshammer et al. 2021)
Tetrahydrocurcumin is a curcumin metabolite credited with additional health – promoting properties. The metabolic bioavailability gives the ratio of the in – vivo production of tetrahydrocurcumin to the absorbed amount of curcumin. Another finding of the long – term study is that, after only four weeks, daily ingestion of CAVACURMIN ® (approx. 340 milligrams curcumin each time) leads to a consistently high blood concentration of curcumin and tetrahydrocurcum in. This effect can be measured after 12 weeks as well. The long – term study furthermore confirmed very high tolerability of CAVACURMIN ®
CAVACURMIN ® can be easily processed in food supplements, such as tablets, capsules and energy bars or functional beverages.