Groupe Berkem, a leading player in bio-based chemistry, announces impressive results for its successful grape seed extract, Biombalance™, in its Health, Beauty & Nutrition Business area. Part of the BeGrape™ range, Biombalance™ is Groupe Berkem’s grape seed extract developed for the Nutraceutical market from carefully selected grapes harvested in the Champagne region (France). Groupe Berkem is a pioneer in polyphenols, and the Group’s R&D department constantly invests in research and proprietary preclinical and human trials to get the most out of OPCs*, exploring their sought-after benefits on human health.
Groupe Berkem will be showcasing Biombalance™ at Vitafoods Asia 2025 (booth C45), underlining its commitment to innovation in nutraceuticals and highlighting its clinically proven benefits for gut health.
Recent scientific studies have shown amazing results: making it the first and only grape seed extract with proven efficacy in promoting gut health and quality of life. “With 72% of volunteers stating they didn’t have to change their diet to avoid discomfort any longer, Biombalance™ supplementation really makes a difference to people’s quality of life. It’s an important breakthrough for the nutraceutical market,” stated Dr. Amandine Brochot, Groupe Berkem Scientific Manager for the Health, Beauty & Nutrition Business area.
Following previous prebiotic results published in Antioxidants Scientific Journal, outstanding benefits from 2 recent clinical trials are now revealed (human pilot study and human study vs placebo), demonstrating:
Proven efficacy after 2 months: In the human study vs. placebo, nearly 8 out of 10 consumers experienced significant relief from occasional digestive upsets such as gas and abdominal bloating.
Rapid results: Noticeable improvements in digestive comfort and quality of life were reported as early as 2 weeks of supplementation, with 500 mg daily intake over 2 months. Three out of four consumers were satisfied with its speed of action after only 4 weeks.
Promotion of digestive comfort: 77% of consumers reported improved digestive well-being with a noticeable reduction of digestive discomfort. Participants who benefit the most in the BiombalanceTM group, are the ones who suffer the most at baseline: 84% of consumers perceived a reduction of the intensity of their digestive discomfort.
Support in quality of life: Most users reported improved mood, energy, and daily well-being,
High satisfaction and recommendation: As a result, over 80% of consumers (up to 98% in the pilot study) declared being satisfied by BiombalanceTM
In conclusion, Biombalance™ stands out in digestive health-promoting ingredients and brings true innovation to brands in the nutraceutical market worldwide:

Biombalance™ is the first and only grape seed extract with proven efficacy on gut health.
It is an innovative plant-based ingredient packed with polyphenols that have a prebiotic effect.
Its results are supported by rigorous proprietary preclinical studies revealing 5 key modes of action with innovative effects on microbiota: prebiotic selective stimulation of good bacteria; positive impact on Short Chain Fatty Acid production; protection against free radicals; supporting intestinal wall barrier function; supporting healthy inflammatory response.
2 human studies demonstrated
Rapid and long-lasting digestive discomfort relief during supplementation.
Trust by consumers (high satisfaction and recommendation rates)
Improvement of quality of life
Nancy Kleperis, Country Manager USA for Groupe Berkem, adds: “The famous French Paradox is no longer proven accurate exclusively for the cardiovascular sphere. It now resonates also when it comes to grape seeds and gut health.””
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