A new peer-reviewed article on the results of the latest clinical study with Bonolive® in menopaused women was published in the international journal
Nutrients. The manuscript is authored by scientists of the departments of Human Biology and Nutrition and Movement Sciences at Maastricht University, the Netherlands and scientists of Solabia Nutrition.
This randomized double-blind placebo-controlled trial aimed to investigate the efect of Bonolive® on Menopausal Symptoms including physical and
psychological domains.
Bonolive®: award-winning olive leaf extract for women’s health
Bonolive® is a clinically validated extract from Manzanilla olive leaves, standardized for 40% oleuropein. In previous published clinical studies in menopaused women, Bonolive® has established its beneficial efects on increasing bone-formation markers, reducing joint pain and improving blood lipid
profile – all key domains for Menopausal women’s quality of life!
The FEMMED study:
Olive Leaf Extract Supplementation Improves Postmenopausal Symptoms: A Randomized, Double-Blind, Placebo-Controlled Parallel Study on Postmenopausal Women
Introduction
Menopause marks the end of a woman’s reproductive years, caused by a decline in ovarian hormone production like estrogen. This gradual process afects various organs like skeletal muscle and skin. Menopause also comes with various physical and psychological symptoms that impact health and quality of life. For example: hot flashes, sleep issues, fatigue, skin dryness and reduced sexual desire. Hormone replacement therapy (HRT) is a popular treatment option, though it has side efects. Therefore, women are looking for a natural and hormone-free solution for menopause symptoms.
Methods
For this RCT, 60 postmenopausal women aged between 47-70 years completed the trial. They took 250mg Bonolive® or placebo daily for 12 weeks and completed measurements at baseline, 6 weeks and 12 weeks. Measurements included DEXA scan, validated Menopause Quality of Life questionnaire (MENQoL), blood samples and more. The full study design can be seen in the publication: https://www.mdpi.com/2072-6643/16/22/3879
Results
The overall MENQoL score was significantly improved (p=0.027) after 6 weeks of Bonolive® intake compared to placebo. This score included Vasomotor,
Psychological, Physical and Sexual domains. This study also confirms Bonolive®’s treatment efect on lowering triglycerides levels (p=0.010) and improving TG/HDL ratio (p=0.029). Moreover, a significant increase in bone mineral density (p=0.019) of the dominant arm was observed after Bonolive® intake, compared to placebo.
Conclusion
The FEMMED study demonstrates the potential of Bonolive® as a 100% natural solution for Menopause care. This is indicated by the significant improvement in menopause symptoms as analyzed via the internationally validated MENQoL Score. Bonolive® ofers consumers a science-based and plant-based solution to address the challenges of Menopause.
Innovations in Food (& Beverage) Technology is a quarterly magazine distributed globally both in Print and Digital formats. www.innovationsfood.com. Twitter: @Innovfoodtech. Instagram: @innovationsinfoodtechnology. Linkedin: www.linkedin.com/in/terry-prior52
